The Central Business District of New Orleans is located immediately north and west of the Mississippi River and was historically called the "American Quarter or American Sector. " Most streets in this area fan out from a central point in the city. Major streets of the area include Canal Street, Poydras Street, Tulane Avenue and Loyola Avenue. In the local parlance "downtown" means "downriver from Canal Street," while "uptown" means "upriver from Canal Street." Other major districts within the city include Bayou St. John, Mid-City, Gentilly, Lakeview, Lakefront, New Orleans East and Algiers.
New Orleans is the home to one of the largest and busiest ports in the world and accounts for a major portion of the nation's refinery and production of petroleum, has a top 50 research university (in Tulane University) as well as half a dozen other institutions of higher education and is renown for its cultural tourism.